B9A064 (IGLL5)

Overview
Predicted structure (AF):
AF-B9A064-F1-model_v4
Uniprot entry:
B9A064
Gene:
IGLL5
Protein length:
214 residues
Mutations found:
4065
Benign based on D2Deep prediction:
3327 out of 4065 mutations
Pathogenic based on D2Deep prediction:
738 out of 4065 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4065 mutations across 214 unique positions. There are 3327 benign and 738 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.001 0.505 View mutations
2 R 19 0 19 0.047 0.663 View mutations
3 P 10 9 19 0.426 0.467 View mutations
4 K 19 0 19 0.029 0.690 View mutations
5 T 19 0 19 0.000 0.651 View mutations
6 G 19 0 19 0.001 0.625 View mutations
7 Q 19 0 19 0.005 0.703 View mutations
8 V 19 0 19 0.003 0.768 View mutations
9 G 19 0 19 0.007 0.751 View mutations
10 C 18 1 19 0.086 0.893 View mutations
11 E 19 0 19 0.006 0.789 View mutations
12 T 19 0 19 0.007 0.717 View mutations
13 P 19 0 19 0.003 0.841 View mutations
14 E 19 0 19 0.036 0.901 View mutations
15 E 19 0 19 0.031 0.767 View mutations
16 L 19 0 19 0.064 0.835 View mutations
17 G 19 0 19 0.005 0.776 View mutations
18 P 19 0 19 0.023 0.845 View mutations
19 G 19 0 19 0.003 0.839 View mutations
20 P 19 0 19 0.001 0.862 View mutations
21 R 19 0 19 0.015 0.849 View mutations
22 Q 18 1 19 0.039 0.830 View mutations
23 R 17 2 19 0.147 0.740 View mutations
24 W 6 13 19 0.653 0.370 View mutations
25 P 12 7 19 0.429 0.501 View mutations