P19256 (CD58)

Overview
Predicted structure (AF):
AF-P19256-F1-model_v4
Uniprot entry:
P19256
Gene:
CD58
Protein length:
250 residues
Mutations found:
4749
Benign based on D2Deep prediction:
4747 out of 4749 mutations
Pathogenic based on D2Deep prediction:
2 out of 4749 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 4749 mutations across 250 unique positions. There are 4747 benign and 2 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 I 19 0 19 0.004 0.772 View mutations
227 T 19 0 19 0.009 0.783 View mutations
228 T 19 0 19 0.006 0.815 View mutations
229 C 19 0 19 0.009 0.729 View mutations
230 I 19 0 19 0.010 0.770 View mutations
231 V 19 0 19 0.013 0.828 View mutations
232 L 19 0 19 0.012 0.761 View mutations
233 Y 19 0 19 0.025 0.726 View mutations
234 M 19 0 19 0.016 0.787 View mutations
235 N 19 0 19 0.019 0.844 View mutations
236 G 19 0 19 0.007 0.685 View mutations
237 I 19 0 19 0.009 0.623 View mutations
238 L 19 0 19 0.015 0.642 View mutations
239 K 19 0 19 0.027 0.546 View mutations
240 C 19 0 19 0.008 0.503 View mutations
241 D 19 0 19 0.017 0.587 View mutations
242 R 19 0 19 0.009 0.497 View mutations
243 K 19 0 19 0.010 0.484 View mutations
244 P 19 0 19 0.041 0.438 View mutations
245 D 19 0 19 0.004 0.359 View mutations
246 R 19 0 19 0.001 0.514 View mutations
247 T 19 0 19 0.001 0.540 View mutations
248 N 19 0 19 0.002 0.510 View mutations
249 S 19 0 19 0.001 0.465 View mutations
250 N 19 0 19 0.007 0.467 View mutations