P26842 (P26842)

Overview
Predicted structure (AF):
AF-P26842-F1-model_v4
Uniprot entry:
P26842
Gene:
P26842
Protein length:
260 residues
Mutations found:
4939
Benign based on D2Deep prediction:
3392 out of 4939 mutations
Pathogenic based on D2Deep prediction:
1547 out of 4939 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4939 mutations across 260 unique positions. There are 3392 benign and 1547 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 V 18 1 19 0.078 0.782 View mutations
227 E 19 0 19 0.000 0.688 View mutations
228 P 18 1 19 0.049 0.630 View mutations
229 A 7 12 19 0.696 0.413 View mutations
230 E 16 3 19 0.174 0.548 View mutations
231 P 18 1 19 0.142 0.630 View mutations
232 C 19 0 19 0.000 0.676 View mutations
233 H 16 3 19 0.226 0.559 View mutations
234 Y 4 15 19 0.739 0.338 View mutations
235 S 19 0 19 0.031 0.479 View mutations
236 C 19 0 19 0.000 0.556 View mutations
237 P 10 9 19 0.527 0.496 View mutations
238 R 0 19 19 0.906 0.438 View mutations
239 E 10 9 19 0.541 0.427 View mutations
240 E 9 10 19 0.543 0.432 View mutations
241 E 19 0 19 0.021 0.390 View mutations
242 G 15 4 19 0.343 0.420 View mutations
243 S 12 7 19 0.364 0.496 View mutations
244 T 18 1 19 0.065 0.438 View mutations
245 I 13 6 19 0.309 0.421 View mutations
246 P 13 6 19 0.325 0.417 View mutations
247 I 17 2 19 0.156 0.482 View mutations
248 Q 0 19 19 0.996 0.500 View mutations
249 E 1 18 19 0.955 0.531 View mutations
250 D 4 15 19 0.775 0.519 View mutations