P27797 (P27797)

Overview
Predicted structure (AF):
AF-P27797-F1-model_v4
Uniprot entry:
P27797
Gene:
P27797
Protein length:
417 residues
Mutations found:
7922
Benign based on D2Deep prediction:
4717 out of 7922 mutations
Pathogenic based on D2Deep prediction:
3205 out of 7922 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7922 mutations across 417 unique positions. There are 4717 benign and 3205 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 S 1 18 19 0.947 0.600 View mutations
127 E 10 9 19 0.481 0.436 View mutations
128 Y 0 19 19 1.000 0.636 View mutations
129 N 8 11 19 0.568 0.434 View mutations
130 I 1 18 19 0.954 0.812 View mutations
131 M 0 19 19 1.000 0.821 View mutations
132 F 0 19 19 1.000 0.902 View mutations
133 G 0 19 19 1.000 0.819 View mutations
134 P 0 19 19 1.000 0.944 View mutations
135 D 6 13 19 0.691 0.655 View mutations
136 I 0 19 19 1.000 0.787 View mutations
137 C 0 19 19 1.000 0.803 View mutations
138 G 0 19 19 0.991 0.778 View mutations
139 P 2 17 19 0.899 0.573 View mutations
140 G 1 18 19 0.933 0.566 View mutations
141 T 0 19 19 0.916 0.605 View mutations
142 K 13 6 19 0.328 0.451 View mutations
143 K 19 0 19 0.000 0.321 View mutations
144 V 0 19 19 0.972 0.730 View mutations
145 H 14 5 19 0.313 0.398 View mutations
146 V 19 0 19 0.029 0.301 View mutations
147 I 0 19 19 0.994 0.712 View mutations
148 F 19 0 19 0.006 0.409 View mutations
149 N 14 5 19 0.290 0.421 View mutations
150 Y 19 0 19 0.000 0.369 View mutations