P50148 (GNAQ)

Overview
Predicted structure (AF):
AF-P50148-F1-model_v4
Uniprot entry:
P50148
Gene:
GNAQ
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
4080 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2740 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 4080 benign and 2740 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 1 17 18 0.819 0.280 View mutations
2 T 19 0 19 0.006 0.755 View mutations
3 L 11 8 19 0.481 0.546 View mutations
4 E 15 4 19 0.242 0.718 View mutations
5 S 19 0 19 0.013 0.899 View mutations
6 I 19 0 19 0.067 1.000 View mutations
7 M 19 0 19 0.010 0.880 View mutations
8 A 19 0 19 0.000 0.825 View mutations
9 C 18 1 19 0.121 0.635 View mutations
10 C 18 1 19 0.076 0.636 View mutations
11 L 19 0 19 0.002 0.740 View mutations
12 S 18 1 19 0.121 0.655 View mutations
13 E 19 0 19 0.004 0.624 View mutations
14 E 19 0 19 0.048 0.609 View mutations
15 A 19 0 19 0.001 0.727 View mutations
16 K 19 0 19 0.003 0.708 View mutations
17 E 17 2 19 0.111 0.571 View mutations
18 A 17 2 19 0.153 0.621 View mutations
19 R 18 1 19 0.048 0.690 View mutations
20 R 19 0 19 0.006 0.579 View mutations
21 I 4 15 19 0.770 0.428 View mutations
22 N 19 0 19 0.013 0.512 View mutations
23 D 18 1 19 0.101 0.651 View mutations
24 E 16 3 19 0.268 0.496 View mutations
25 I 3 16 19 0.827 0.537 View mutations