Q01081 (U2AF1)

Overview
Predicted structure (AF):
AF-Q01081-F1-model_v4
Uniprot entry:
Q01081
Gene:
U2AF1
Protein length:
240 residues
Mutations found:
4559
Benign based on D2Deep prediction:
2811 out of 4559 mutations
Pathogenic based on D2Deep prediction:
1748 out of 4559 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 4559 mutations across 240 unique positions. There are 2811 benign and 1748 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 R 11 8 19 0.387 0.456 View mutations
152 E 0 19 19 1.000 0.893 View mutations
153 A 3 16 19 0.839 0.756 View mutations
154 C 16 3 19 0.190 0.381 View mutations
155 C 0 19 19 1.000 0.813 View mutations
156 R 12 7 19 0.389 0.443 View mutations
157 Q 5 14 19 0.616 0.588 View mutations
158 Y 3 16 19 0.803 0.667 View mutations
159 E 2 17 19 0.882 0.668 View mutations
160 M 18 1 19 0.078 0.483 View mutations
161 G 9 10 19 0.488 0.503 View mutations
162 E 3 16 19 0.822 0.532 View mutations
163 C 0 19 19 0.999 0.752 View mutations
164 T 15 4 19 0.240 0.477 View mutations
165 R 17 2 19 0.105 0.343 View mutations
166 G 6 13 19 0.725 0.610 View mutations
167 G 19 0 19 0.003 0.207 View mutations
168 F 6 13 19 0.662 0.600 View mutations
169 C 10 9 19 0.520 0.484 View mutations
170 N 15 4 19 0.287 0.274 View mutations
171 F 0 19 19 1.000 0.837 View mutations
172 M 6 13 19 0.724 0.613 View mutations
173 H 12 7 19 0.368 0.430 View mutations
174 L 19 0 19 0.035 0.216 View mutations
175 K 11 8 19 0.462 0.470 View mutations