Q02978 (Q02978)

Overview
Predicted structure (AF):
AF-Q02978-F1-model_v4
Uniprot entry:
Q02978
Gene:
Q02978
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3321 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2644 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5965 mutations across 314 unique positions. There are 3321 benign and 2644 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 S 1 18 19 0.960 0.763 View mutations
227 M 15 4 19 0.222 0.393 View mutations
228 I 7 12 19 0.601 0.441 View mutations
229 S 0 19 19 1.000 0.749 View mutations
230 G 1 18 19 0.950 0.712 View mutations
231 L 8 11 19 0.606 0.532 View mutations
232 V 5 14 19 0.745 0.457 View mutations
233 T 0 19 19 1.000 0.668 View mutations
234 T 0 19 19 1.000 0.668 View mutations
235 A 15 4 19 0.230 0.495 View mutations
236 A 19 0 19 0.011 0.393 View mutations
237 S 0 19 19 0.999 0.769 View mutations
238 M 1 18 19 0.952 0.690 View mutations
239 P 0 19 19 1.000 0.760 View mutations
240 V 3 16 19 0.805 0.614 View mutations
241 D 2 17 19 0.803 0.773 View mutations
242 I 2 17 19 0.900 0.704 View mutations
243 A 8 11 19 0.608 0.520 View mutations
244 K 14 5 19 0.293 0.375 View mutations
245 T 3 16 19 0.840 0.715 View mutations
246 R 1 18 19 0.886 0.608 View mutations
247 I 19 0 19 0.028 0.389 View mutations
248 Q 0 19 19 1.000 0.792 View mutations
249 N 1 18 19 0.949 0.705 View mutations
250 M 6 13 19 0.739 0.538 View mutations