Q05923 (Q05923)

Overview
Predicted structure (AF):
AF-Q05923-F1-model_v4
Uniprot entry:
Q05923
Gene:
Q05923
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3261 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2704 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5965 mutations across 314 unique positions. There are 3261 benign and 2704 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 I 2 17 19 0.735 0.614 View mutations
177 L 12 7 19 0.473 0.471 View mutations
178 P 1 18 19 0.839 0.639 View mutations
179 Y 2 17 19 0.894 0.522 View mutations
180 L 3 16 19 0.798 0.586 View mutations
181 F 12 7 19 0.331 0.492 View mutations
182 L 9 10 19 0.518 0.504 View mutations
183 G 2 17 19 0.909 0.576 View mutations
184 S 0 19 19 0.992 0.555 View mutations
185 C 10 9 19 0.471 0.499 View mutations
186 S 15 4 19 0.201 0.471 View mutations
187 H 0 19 19 0.978 0.516 View mutations
188 S 0 19 19 0.948 0.575 View mutations
189 S 1 18 19 0.943 0.483 View mutations
190 D 0 19 19 0.981 0.407 View mutations
191 L 0 19 19 0.957 0.419 View mutations
192 Q 18 1 19 0.147 0.448 View mutations
193 G 4 15 19 0.708 0.422 View mutations
194 L 0 19 19 1.000 0.546 View mutations
195 Q 17 2 19 0.216 0.525 View mutations
196 A 18 1 19 0.046 0.551 View mutations
197 C 12 7 19 0.410 0.441 View mutations
198 G 0 19 19 0.999 0.575 View mutations
199 I 1 18 19 0.960 0.620 View mutations
200 T 0 19 19 1.000 0.625 View mutations