Q06609 (RAD51)

Overview
Predicted structure (AF):
AF-Q06609-F1-model_v4
Uniprot entry:
Q06609
Gene:
RAD51
Protein length:
339 residues
Mutations found:
6440
Benign based on D2Deep prediction:
3846 out of 6440 mutations
Pathogenic based on D2Deep prediction:
2594 out of 6440 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 6440 mutations across 339 unique positions. There are 3846 benign and 2594 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 S 19 0 19 0.005 0.665 View mutations
27 R 19 0 19 0.004 0.663 View mutations
28 L 15 4 19 0.277 0.564 View mutations
29 E 19 0 19 0.007 0.546 View mutations
30 Q 19 0 19 0.000 0.636 View mutations
31 C 19 0 19 0.002 0.675 View mutations
32 G 19 0 19 0.017 0.457 View mutations
33 I 6 13 19 0.687 0.422 View mutations
34 N 19 0 19 0.004 0.567 View mutations
35 A 17 2 19 0.111 0.543 View mutations
36 N 19 0 19 0.001 0.497 View mutations
37 D 19 0 19 0.004 0.393 View mutations
38 V 9 10 19 0.532 0.439 View mutations
39 K 14 5 19 0.210 0.518 View mutations
40 K 19 0 19 0.020 0.468 View mutations
41 L 5 14 19 0.729 0.439 View mutations
42 E 18 1 19 0.043 0.517 View mutations
43 E 19 0 19 0.000 0.414 View mutations
44 A 16 3 19 0.155 0.430 View mutations
45 G 0 19 19 1.000 0.467 View mutations
46 F 3 16 19 0.776 0.423 View mutations
47 H 18 1 19 0.060 0.407 View mutations
48 T 9 10 19 0.565 0.501 View mutations
49 V 8 11 19 0.509 0.501 View mutations
50 E 3 16 19 0.849 0.476 View mutations