Q06609 (RAD51)

Overview
Predicted structure (AF):
AF-Q06609-F1-model_v4
Uniprot entry:
Q06609
Gene:
RAD51
Protein length:
339 residues
Mutations found:
6440
Benign based on D2Deep prediction:
3846 out of 6440 mutations
Pathogenic based on D2Deep prediction:
2594 out of 6440 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 6440 mutations across 339 unique positions. There are 3846 benign and 2594 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 F 1 18 19 0.943 0.763 View mutations
127 G 0 19 19 0.999 0.930 View mutations
128 E 0 19 19 1.000 0.874 View mutations
129 F 1 18 19 0.945 0.742 View mutations
130 R 0 19 19 1.000 0.870 View mutations
131 T 2 17 19 0.919 0.772 View mutations
132 G 0 19 19 1.000 0.958 View mutations
133 K 0 19 19 1.000 0.849 View mutations
134 T 1 18 19 0.948 0.802 View mutations
135 Q 1 18 19 0.885 0.801 View mutations
136 I 3 16 19 0.856 0.640 View mutations
137 C 2 17 19 0.909 0.631 View mutations
138 H 0 19 19 0.997 0.710 View mutations
139 T 6 13 19 0.681 0.567 View mutations
140 L 1 18 19 0.951 0.695 View mutations
141 A 4 15 19 0.808 0.610 View mutations
142 V 19 0 19 0.095 0.236 View mutations
143 T 19 0 19 0.000 0.309 View mutations
144 C 5 14 19 0.756 0.605 View mutations
145 Q 12 7 19 0.398 0.401 View mutations
146 L 19 0 19 0.000 0.365 View mutations
147 P 12 7 19 0.419 0.493 View mutations
148 I 19 0 19 0.000 0.464 View mutations
149 D 19 0 19 0.013 0.464 View mutations
150 R 19 0 19 0.000 0.575 View mutations