O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 E 13 6 19 0.319 0.415 View mutations
352 A 14 5 19 0.265 0.353 View mutations
353 Y 17 2 19 0.116 0.395 View mutations
354 R 19 0 19 0.028 0.477 View mutations
355 S 19 0 19 0.010 0.333 View mutations
356 L 19 0 19 0.000 0.178 View mutations
357 A 19 0 19 0.001 0.342 View mutations
358 S 14 5 19 0.344 0.408 View mutations
359 A 14 5 19 0.254 0.466 View mutations
360 Q 19 0 19 0.000 0.413 View mutations
361 C 19 0 19 0.000 0.591 View mutations
362 P 19 0 19 0.018 0.565 View mutations
363 F 15 4 19 0.248 0.456 View mutations
364 L 13 6 19 0.295 0.464 View mutations
365 G 19 0 19 0.011 0.579 View mutations
366 P 19 0 19 0.016 0.576 View mutations
367 P 19 0 19 0.001 0.463 View mutations
368 R 13 6 19 0.263 0.506 View mutations
369 K 19 0 19 0.017 0.582 View mutations
370 R 19 0 19 0.000 0.557 View mutations
371 L 19 0 19 0.026 0.524 View mutations
372 K 19 0 19 0.000 0.530 View mutations
373 Q 17 2 19 0.122 0.577 View mutations
374 S 19 0 19 0.002 0.512 View mutations