O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 N 19 0 19 0.000 0.430 View mutations
302 A 19 0 19 0.000 0.348 View mutations
303 A 11 8 19 0.459 0.492 View mutations
304 E 14 5 19 0.235 0.402 View mutations
305 I 19 0 19 0.000 0.425 View mutations
306 L 3 16 19 0.802 0.795 View mutations
307 I 19 0 19 0.002 0.349 View mutations
308 L 19 0 19 0.005 0.213 View mutations
309 A 19 0 19 0.017 0.000 View mutations
310 D 1 18 19 0.921 0.874 View mutations
311 L 17 2 19 0.107 0.201 View mutations
312 H 19 0 19 0.000 0.184 View mutations
313 S 19 0 19 0.000 0.236 View mutations
314 A 9 10 19 0.484 0.507 View mutations
315 D 19 0 19 0.029 0.343 View mutations
316 Q 19 0 19 0.001 0.346 View mutations
317 L 4 15 19 0.710 0.669 View mutations
318 K 19 0 19 0.001 0.257 View mutations
319 T 18 1 19 0.059 0.427 View mutations
320 Q 19 0 19 0.008 0.375 View mutations
321 A 17 2 19 0.137 0.309 View mutations
322 V 13 6 19 0.340 0.407 View mutations
323 D 19 0 19 0.001 0.343 View mutations
324 F 2 17 19 0.905 0.782 View mutations
325 I 2 17 19 0.879 0.780 View mutations