P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.001 0.587 View mutations
2 E 18 1 19 0.063 0.763 View mutations
3 P 14 5 19 0.258 0.609 View mutations
4 P 18 1 19 0.036 0.763 View mutations
5 R 19 0 19 0.009 0.758 View mutations
6 G 19 0 19 0.000 0.800 View mutations
7 P 19 0 19 0.000 0.823 View mutations
8 P 19 0 19 0.001 0.804 View mutations
9 A 19 0 19 0.002 0.833 View mutations
10 N 19 0 19 0.011 0.821 View mutations
11 G 19 0 19 0.001 0.766 View mutations
12 A 19 0 19 0.003 0.798 View mutations
13 E 19 0 19 0.018 0.737 View mutations
14 P 19 0 19 0.011 0.703 View mutations
15 S 19 0 19 0.002 0.718 View mutations
16 R 19 0 19 0.000 0.623 View mutations
17 A 19 0 19 0.002 0.638 View mutations
18 V 18 1 19 0.059 0.670 View mutations
19 G 19 0 19 0.002 0.679 View mutations
20 T 19 0 19 0.001 0.642 View mutations
21 V 4 15 19 0.829 0.400 View mutations
22 K 13 6 19 0.333 0.455 View mutations
23 V 3 16 19 0.851 0.404 View mutations
24 Y 3 16 19 0.779 0.393 View mutations
25 L 0 19 19 0.982 0.503 View mutations