P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 P 0 19 19 0.999 0.543 View mutations
27 N 1 18 19 0.880 0.508 View mutations
28 K 18 1 19 0.075 0.409 View mutations
29 Q 1 18 19 0.948 0.511 View mutations
30 R 2 17 19 0.871 0.448 View mutations
31 T 9 10 19 0.535 0.501 View mutations
32 V 13 6 19 0.299 0.419 View mutations
33 V 0 19 19 0.991 0.508 View mutations
34 T 19 0 19 0.095 0.444 View mutations
35 V 4 15 19 0.737 0.429 View mutations
36 R 19 0 19 0.029 0.388 View mutations
37 D 18 1 19 0.068 0.364 View mutations
38 G 6 13 19 0.704 0.505 View mutations
39 M 7 12 19 0.630 0.430 View mutations
40 S 7 12 19 0.619 0.434 View mutations
41 V 1 18 19 0.931 0.457 View mutations
42 Y 18 1 19 0.045 0.518 View mutations
43 D 16 3 19 0.174 0.437 View mutations
44 S 2 17 19 0.873 0.436 View mutations
45 L 0 19 19 1.000 0.484 View mutations
46 D 18 1 19 0.119 0.409 View mutations
47 K 1 18 19 0.900 0.533 View mutations
48 A 0 19 19 0.998 0.545 View mutations
49 L 3 16 19 0.857 0.530 View mutations
50 K 6 13 19 0.690 0.501 View mutations