P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 R 19 0 19 0.070 0.631 View mutations
152 Q 18 1 19 0.043 0.658 View mutations
153 Q 19 0 19 0.005 0.726 View mutations
154 F 19 0 19 0.036 0.713 View mutations
155 Y 17 2 19 0.160 0.697 View mutations
156 H 19 0 19 0.004 0.788 View mutations
157 S 19 0 19 0.003 0.806 View mutations
158 V 19 0 19 0.033 0.787 View mutations
159 Q 19 0 19 0.000 0.787 View mutations
160 D 19 0 19 0.001 0.812 View mutations
161 L 19 0 19 0.002 0.798 View mutations
162 S 19 0 19 0.012 0.847 View mutations
163 G 19 0 19 0.003 0.862 View mutations
164 G 19 0 19 0.003 0.881 View mutations
165 S 19 0 19 0.002 0.871 View mutations
166 R 19 0 19 0.006 0.878 View mutations
167 Q 19 0 19 0.003 0.863 View mutations
168 H 19 0 19 0.002 0.824 View mutations
169 E 19 0 19 0.005 0.857 View mutations
170 A 19 0 19 0.009 0.858 View mutations
171 P 18 1 19 0.065 0.778 View mutations
172 S 19 0 19 0.004 0.848 View mutations
173 N 19 0 19 0.001 0.845 View mutations
174 R 19 0 19 0.002 0.828 View mutations
175 P 19 0 19 0.002 0.904 View mutations