P10415 (BCL2) at position 21

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19 mutations found: 2 benign and 17 pathogenic.

D2Deep score mean: 0.898. Overall confidence mean: 0.674

Identifier Original Position Target D2Deep Prediction Pred. Interpretation Overall confidence Actions
Y21A Y 21 A 0.990 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21C Y 21 C 0.271 Benign based on D2Deep prediction 0.280 View mutation
Y21D Y 21 D 0.999 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21E Y 21 E 0.997 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21F Y 21 F 0.991 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21G Y 21 G 0.829 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21H Y 21 H 0.092 Benign based on D2Deep prediction 0.280 View mutation
Y21I Y 21 I 0.944 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21K Y 21 K 0.991 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21L Y 21 L 0.999 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21M Y 21 M 0.999 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21N Y 21 N 0.988 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21P Y 21 P 1.000 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21Q Y 21 Q 0.996 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21R Y 21 R 0.997 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21S Y 21 S 0.988 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21T Y 21 T 0.998 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21V Y 21 V 0.998 Pathogenic based on D2Deep prediction 0.720 View mutation
Y21W Y 21 W 0.994 Pathogenic based on D2Deep prediction 0.720 View mutation