P29992 (GNA11)

Overview
Predicted structure (AF):
AF-P29992-F1-model_v4
Uniprot entry:
P29992
Gene:
GNA11
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
3997 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2823 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 3997 benign and 2823 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 1 17 18 0.813 0.279 View mutations
2 T 19 0 19 0.032 0.752 View mutations
3 L 7 12 19 0.602 0.385 View mutations
4 E 13 6 19 0.398 0.629 View mutations
5 S 18 1 19 0.049 0.882 View mutations
6 M 18 1 19 0.129 0.947 View mutations
7 M 19 0 19 0.000 0.884 View mutations
8 A 19 0 19 0.000 0.804 View mutations
9 C 16 3 19 0.205 0.564 View mutations
10 C 19 0 19 0.013 0.618 View mutations
11 L 19 0 19 0.000 0.724 View mutations
12 S 16 3 19 0.192 0.602 View mutations
13 D 19 0 19 0.026 0.600 View mutations
14 E 17 2 19 0.155 0.570 View mutations
15 V 19 0 19 0.019 0.724 View mutations
16 K 18 1 19 0.059 0.682 View mutations
17 E 15 4 19 0.212 0.537 View mutations
18 S 17 2 19 0.157 0.619 View mutations
19 K 19 0 19 0.024 0.686 View mutations
20 R 19 0 19 0.001 0.563 View mutations
21 I 3 16 19 0.851 0.438 View mutations
22 N 19 0 19 0.022 0.499 View mutations
23 A 17 2 19 0.115 0.624 View mutations
24 E 7 12 19 0.567 0.428 View mutations
25 I 2 17 19 0.882 0.549 View mutations