P29992 (GNA11)

Overview
Predicted structure (AF):
AF-P29992-F1-model_v4
Uniprot entry:
P29992
Gene:
GNA11
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
3997 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2823 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 3997 benign and 2823 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 H 19 0 19 0.003 0.676 View mutations
127 Q 19 0 19 0.011 0.732 View mutations
128 Y 11 8 19 0.462 0.464 View mutations
129 V 19 0 19 0.000 0.557 View mutations
130 S 18 1 19 0.069 0.598 View mutations
131 A 11 8 19 0.418 0.462 View mutations
132 I 5 14 19 0.775 0.578 View mutations
133 K 17 2 19 0.187 0.535 View mutations
134 T 18 1 19 0.053 0.636 View mutations
135 L 19 0 19 0.006 0.363 View mutations
136 W 4 15 19 0.726 0.618 View mutations
137 E 17 2 19 0.078 0.420 View mutations
138 D 14 5 19 0.253 0.463 View mutations
139 P 19 0 19 0.004 0.442 View mutations
140 G 3 16 19 0.864 0.567 View mutations
141 I 14 5 19 0.322 0.403 View mutations
142 Q 19 0 19 0.000 0.390 View mutations
143 E 19 0 19 0.009 0.520 View mutations
144 C 7 12 19 0.623 0.523 View mutations
145 Y 19 0 19 0.017 0.400 View mutations
146 D 19 0 19 0.000 0.496 View mutations
147 R 0 19 19 0.993 0.629 View mutations
148 R 19 0 19 0.000 0.355 View mutations
149 R 19 0 19 0.003 0.335 View mutations
150 E 19 0 19 0.001 0.201 View mutations