P40259 (CD79B)

Overview
Predicted structure (AF):
AF-P40259-F1-model_v4
Uniprot entry:
P40259
Gene:
CD79B
Protein length:
229 residues
Mutations found:
4350
Benign based on D2Deep prediction:
2649 out of 4350 mutations
Pathogenic based on D2Deep prediction:
1701 out of 4350 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 4350 mutations across 229 unique positions. There are 2649 benign and 1701 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 7 11 18 0.596 0.413 View mutations
2 A 14 5 19 0.320 0.607 View mutations
3 R 6 13 19 0.683 0.363 View mutations
4 L 19 0 19 0.060 0.804 View mutations
5 A 19 0 19 0.014 0.833 View mutations
6 L 19 0 19 0.002 0.822 View mutations
7 S 19 0 19 0.001 0.860 View mutations
8 P 19 0 19 0.027 0.867 View mutations
9 V 19 0 19 0.047 0.857 View mutations
10 P 18 1 19 0.080 0.869 View mutations
11 S 19 0 19 0.002 0.948 View mutations
12 H 17 2 19 0.137 0.837 View mutations
13 W 11 8 19 0.408 0.559 View mutations
14 M 16 3 19 0.212 0.787 View mutations
15 V 19 0 19 0.048 0.927 View mutations
16 A 19 0 19 0.003 0.942 View mutations
17 L 18 1 19 0.043 0.807 View mutations
18 L 17 2 19 0.143 0.746 View mutations
19 L 17 2 19 0.193 0.775 View mutations
20 L 19 0 19 0.003 0.851 View mutations
21 L 16 3 19 0.182 0.767 View mutations
22 S 18 1 19 0.070 0.871 View mutations
23 A 17 2 19 0.122 0.838 View mutations
24 E 7 12 19 0.515 0.376 View mutations
25 P 7 12 19 0.545 0.371 View mutations