P40259 (CD79B)

Overview
Predicted structure (AF):
AF-P40259-F1-model_v4
Uniprot entry:
P40259
Gene:
CD79B
Protein length:
229 residues
Mutations found:
4350
Benign based on D2Deep prediction:
2649 out of 4350 mutations
Pathogenic based on D2Deep prediction:
1701 out of 4350 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4350 mutations across 229 unique positions. There are 2649 benign and 1701 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 P 3 16 19 0.809 0.736 View mutations
177 I 5 14 19 0.738 0.664 View mutations
178 F 11 8 19 0.497 0.441 View mutations
179 L 10 9 19 0.516 0.477 View mutations
180 L 9 10 19 0.621 0.522 View mutations
181 L 9 10 19 0.553 0.521 View mutations
182 D 10 9 19 0.516 0.486 View mutations
183 K 0 19 19 0.948 0.545 View mutations
184 D 9 10 19 0.479 0.511 View mutations
185 D 19 0 19 0.024 0.371 View mutations
186 S 19 0 19 0.001 0.435 View mutations
187 K 9 10 19 0.546 0.435 View mutations
188 A 18 1 19 0.141 0.459 View mutations
189 G 2 17 19 0.871 0.605 View mutations
190 M 2 17 19 0.903 0.568 View mutations
191 E 0 19 19 0.999 0.614 View mutations
192 E 1 18 19 0.929 0.636 View mutations
193 D 0 19 19 0.999 0.800 View mutations
194 H 0 19 19 0.995 0.794 View mutations
195 T 0 19 19 0.997 0.826 View mutations
196 Y 0 19 19 1.000 0.779 View mutations
197 E 0 19 19 1.000 0.778 View mutations
198 G 0 19 19 0.983 0.875 View mutations
199 L 1 18 19 0.943 0.802 View mutations
200 D 1 18 19 0.907 0.669 View mutations