P40337 (VHL) at position 21

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19 mutations found: 14 benign and 5 pathogenic.

D2Deep score mean: 0.237. Overall confidence mean: 0.693

Identifier Original Position Target D2Deep Prediction Pred. Interpretation Overall confidence Actions
E21A E 21 A 0.926 Pathogenic based on D2Deep prediction 0.063 View mutation
E21C E 21 C 0.009 Benign based on D2Deep prediction 0.918 View mutation
E21D E 21 D 0.619 Pathogenic based on D2Deep prediction 0.063 View mutation
E21F E 21 F 0.105 Benign based on D2Deep prediction 0.918 View mutation
E21G E 21 G 0.163 Benign based on D2Deep prediction 0.918 View mutation
E21H E 21 H 0.523 Pathogenic based on D2Deep prediction 0.063 View mutation
E21I E 21 I 0.242 Benign based on D2Deep prediction 0.918 View mutation
E21K E 21 K 0.042 Benign based on D2Deep prediction 0.918 View mutation
E21L E 21 L 0.066 Benign based on D2Deep prediction 0.918 View mutation
E21M E 21 M 0.002 Benign based on D2Deep prediction 0.918 View mutation
E21N E 21 N 0.538 Pathogenic based on D2Deep prediction 0.063 View mutation
E21P E 21 P 0.670 Pathogenic based on D2Deep prediction 0.063 View mutation
E21Q E 21 Q 0.306 Benign based on D2Deep prediction 0.918 View mutation
E21R E 21 R 0.080 Benign based on D2Deep prediction 0.918 View mutation
E21S E 21 S 0.025 Benign based on D2Deep prediction 0.918 View mutation
E21T E 21 T 0.004 Benign based on D2Deep prediction 0.918 View mutation
E21V E 21 V 0.025 Benign based on D2Deep prediction 0.918 View mutation
E21W E 21 W 0.024 Benign based on D2Deep prediction 0.918 View mutation
E21Y E 21 Y 0.135 Benign based on D2Deep prediction 0.918 View mutation