P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 S 19 0 19 0.001 0.897 View mutations
27 Y 19 0 19 0.006 0.880 View mutations
28 A 19 0 19 0.007 0.936 View mutations
29 S 19 0 19 0.002 0.855 View mutations
30 S 19 0 19 0.015 0.822 View mutations
31 T 19 0 19 0.005 0.855 View mutations
32 P 19 0 19 0.008 0.793 View mutations
33 L 12 7 19 0.436 0.564 View mutations
34 H 18 1 19 0.071 0.740 View mutations
35 V 17 2 19 0.155 0.707 View mutations
36 P 18 1 19 0.051 0.752 View mutations
37 V 19 0 19 0.002 0.771 View mutations
38 P 18 1 19 0.056 0.782 View mutations
39 R 18 1 19 0.069 0.806 View mutations
40 A 18 1 19 0.059 0.791 View mutations
41 L 16 3 19 0.247 0.700 View mutations
42 R 19 0 19 0.004 0.805 View mutations
43 M 19 0 19 0.005 0.802 View mutations
44 E 15 4 19 0.256 0.613 View mutations
45 E 3 16 19 0.817 0.283 View mutations
46 D 18 1 19 0.076 0.766 View mutations
47 S 19 0 19 0.007 0.800 View mutations
48 I 19 0 19 0.002 0.839 View mutations
49 R 19 0 19 0.021 0.735 View mutations
50 L 6 13 19 0.681 0.384 View mutations