P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 P 2 17 19 0.760 0.285 View mutations
52 A 14 5 19 0.285 0.567 View mutations
53 H 3 16 19 0.834 0.309 View mutations
54 L 3 16 19 0.828 0.315 View mutations
55 R 16 3 19 0.145 0.586 View mutations
56 L 4 15 19 0.770 0.393 View mutations
57 Q 0 19 19 0.956 0.347 View mutations
58 P 1 18 19 0.944 0.455 View mutations
59 I 14 5 19 0.311 0.439 View mutations
60 Y 7 12 19 0.663 0.433 View mutations
61 W 0 19 19 1.000 0.516 View mutations
62 S 0 19 19 0.982 0.583 View mutations
63 R 15 4 19 0.319 0.472 View mutations
64 D 4 15 19 0.781 0.504 View mutations
65 D 0 19 19 1.000 0.609 View mutations
66 V 3 16 19 0.844 0.563 View mutations
67 A 7 12 19 0.623 0.502 View mutations
68 Q 3 16 19 0.822 0.468 View mutations
69 W 0 19 19 0.997 0.653 View mutations
70 L 3 16 19 0.841 0.616 View mutations
71 K 2 17 19 0.870 0.468 View mutations
72 W 0 19 19 0.991 0.680 View mutations
73 A 0 19 19 0.998 0.716 View mutations
74 E 0 19 19 1.000 0.677 View mutations
75 N 6 13 19 0.653 0.440 View mutations