P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 D 19 0 19 0.004 0.152 View mutations
102 F 19 0 19 0.061 0.181 View mutations
103 R 13 6 19 0.358 0.389 View mutations
104 Y 1 18 19 0.913 0.715 View mutations
105 R 0 19 19 0.972 0.722 View mutations
106 S 5 14 19 0.717 0.593 View mutations
107 P 0 19 19 0.927 0.745 View mutations
108 H 13 6 19 0.337 0.479 View mutations
109 S 15 4 19 0.246 0.388 View mutations
110 G 3 16 19 0.851 0.676 View mutations
111 D 1 18 19 0.901 0.653 View mutations
112 V 8 11 19 0.621 0.523 View mutations
113 L 6 13 19 0.657 0.570 View mutations
114 Y 13 6 19 0.365 0.439 View mutations
115 E 2 17 19 0.787 0.607 View mutations
116 L 14 5 19 0.277 0.467 View mutations
117 L 2 17 19 0.868 0.600 View mutations
118 Q 18 1 19 0.076 0.436 View mutations
119 H 17 2 19 0.170 0.489 View mutations
120 I 13 6 19 0.323 0.483 View mutations
121 L 3 16 19 0.867 0.578 View mutations
122 K 9 10 19 0.482 0.433 View mutations
123 Q 3 16 19 0.822 0.425 View mutations
124 R 5 14 19 0.694 0.433 View mutations
125 K 17 2 19 0.144 0.542 View mutations