P49715 (CEBPA)

Overview
Predicted structure (AF):
AF-P49715-F1-model_v4
Uniprot entry:
P49715
Gene:
CEBPA
Protein length:
358 residues
Mutations found:
6801
Benign based on D2Deep prediction:
3331 out of 6801 mutations
Pathogenic based on D2Deep prediction:
3470 out of 6801 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6801 mutations across 358 unique positions. There are 3331 benign and 3470 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 0 18 18 0.997 0.601 View mutations
2 E 1 18 19 0.890 0.592 View mutations
3 S 1 18 19 0.939 0.511 View mutations
4 A 1 18 19 0.940 0.566 View mutations
5 D 11 8 19 0.464 0.486 View mutations
6 F 6 13 19 0.662 0.535 View mutations
7 Y 6 13 19 0.625 0.537 View mutations
8 E 17 2 19 0.226 0.407 View mutations
9 A 19 0 19 0.068 0.353 View mutations
10 E 15 4 19 0.328 0.494 View mutations
11 P 19 0 19 0.042 0.480 View mutations
12 R 9 10 19 0.506 0.432 View mutations
13 P 16 3 19 0.191 0.457 View mutations
14 P 15 4 19 0.201 0.474 View mutations
15 M 16 3 19 0.241 0.527 View mutations
16 S 19 0 19 0.004 0.502 View mutations
17 S 18 1 19 0.059 0.523 View mutations
18 H 16 3 19 0.177 0.561 View mutations
19 L 7 12 19 0.627 0.410 View mutations
20 Q 18 1 19 0.036 0.620 View mutations
21 S 12 7 19 0.452 0.530 View mutations
22 P 5 14 19 0.730 0.356 View mutations
23 P 12 7 19 0.356 0.547 View mutations
24 H 1 18 19 0.809 0.199 View mutations
25 A 6 13 19 0.670 0.374 View mutations