P49715 (CEBPA)

Overview
Predicted structure (AF):
AF-P49715-F1-model_v4
Uniprot entry:
P49715
Gene:
CEBPA
Protein length:
358 residues
Mutations found:
6801
Benign based on D2Deep prediction:
3331 out of 6801 mutations
Pathogenic based on D2Deep prediction:
3470 out of 6801 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6801 mutations across 358 unique positions. There are 3331 benign and 3470 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 P 1 18 19 0.942 0.448 View mutations
52 L 0 19 19 0.969 0.410 View mutations
53 G 1 18 19 0.917 0.462 View mutations
54 G 3 16 19 0.786 0.532 View mutations
55 I 4 15 19 0.782 0.466 View mutations
56 C 1 18 19 0.880 0.599 View mutations
57 E 0 19 19 0.994 0.681 View mutations
58 H 0 19 19 0.995 0.657 View mutations
59 E 0 19 19 1.000 0.711 View mutations
60 T 0 19 19 0.999 0.714 View mutations
61 S 0 19 19 1.000 0.776 View mutations
62 I 0 19 19 1.000 0.734 View mutations
63 D 0 19 19 1.000 0.786 View mutations
64 I 1 18 19 0.944 0.714 View mutations
65 S 1 18 19 0.926 0.838 View mutations
66 A 2 17 19 0.838 0.863 View mutations
67 Y 0 19 19 0.997 0.828 View mutations
68 I 1 18 19 0.965 0.789 View mutations
69 D 0 19 19 1.000 0.894 View mutations
70 P 0 19 19 1.000 0.969 View mutations
71 A 0 19 19 0.998 0.828 View mutations
72 A 0 19 19 1.000 0.930 View mutations
73 F 0 19 19 1.000 0.832 View mutations
74 N 0 19 19 1.000 0.901 View mutations
75 D 0 19 19 1.000 0.856 View mutations