P58012 (P58012)

Overview
Predicted structure (AF):
AF-P58012-F1-model_v4
Uniprot entry:
P58012
Gene:
P58012
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4360 out of 7143 mutations
Pathogenic based on D2Deep prediction:
2783 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4360 benign and 2783 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 P 17 2 19 0.115 0.728 View mutations
252 A 14 5 19 0.319 0.651 View mutations
253 A 5 14 19 0.666 0.323 View mutations
254 S 17 2 19 0.112 0.683 View mutations
255 Y 3 16 19 0.848 0.364 View mutations
256 G 10 9 19 0.488 0.477 View mutations
257 P 1 18 19 0.882 0.313 View mutations
258 Y 5 14 19 0.655 0.384 View mutations
259 T 17 2 19 0.132 0.589 View mutations
260 R 15 4 19 0.232 0.539 View mutations
261 V 16 3 19 0.153 0.605 View mutations
262 Q 0 19 19 0.996 0.249 View mutations
263 S 8 11 19 0.542 0.428 View mutations
264 M 16 3 19 0.175 0.640 View mutations
265 A 18 1 19 0.069 0.650 View mutations
266 L 19 0 19 0.036 0.651 View mutations
267 P 5 14 19 0.714 0.336 View mutations
268 P 13 6 19 0.335 0.543 View mutations
269 G 8 11 19 0.520 0.429 View mutations
270 V 8 11 19 0.608 0.429 View mutations
271 V 10 9 19 0.449 0.475 View mutations
272 N 18 1 19 0.129 0.594 View mutations
273 S 19 0 19 0.031 0.611 View mutations
274 Y 8 11 19 0.615 0.431 View mutations
275 N 17 2 19 0.117 0.652 View mutations