P58012 (P58012)

Overview
Predicted structure (AF):
AF-P58012-F1-model_v4
Uniprot entry:
P58012
Gene:
P58012
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4360 out of 7143 mutations
Pathogenic based on D2Deep prediction:
2783 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4360 benign and 2783 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.005 0.635 View mutations
2 M 12 7 19 0.429 0.520 View mutations
3 A 4 15 19 0.752 0.341 View mutations
4 S 12 7 19 0.391 0.527 View mutations
5 Y 19 0 19 0.078 0.708 View mutations
6 P 18 1 19 0.039 0.738 View mutations
7 E 19 0 19 0.029 0.807 View mutations
8 P 19 0 19 0.049 0.790 View mutations
9 E 18 1 19 0.100 0.681 View mutations
10 D 18 1 19 0.115 0.698 View mutations
11 A 17 2 19 0.088 0.699 View mutations
12 A 11 8 19 0.388 0.519 View mutations
13 G 19 0 19 0.018 0.809 View mutations
14 A 15 4 19 0.246 0.628 View mutations
15 L 19 0 19 0.013 0.736 View mutations
16 L 19 0 19 0.017 0.765 View mutations
17 A 17 2 19 0.142 0.717 View mutations
18 P 18 1 19 0.084 0.768 View mutations
19 E 17 2 19 0.129 0.731 View mutations
20 T 15 4 19 0.233 0.707 View mutations
21 G 14 5 19 0.321 0.689 View mutations
22 R 19 0 19 0.027 0.910 View mutations
23 T 11 8 19 0.416 0.560 View mutations
24 V 19 0 19 0.026 0.957 View mutations
25 K 19 0 19 0.003 0.925 View mutations