P58012 (P58012)

Overview
Predicted structure (AF):
AF-P58012-F1-model_v4
Uniprot entry:
P58012
Gene:
P58012
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4360 out of 7143 mutations
Pathogenic based on D2Deep prediction:
2783 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4360 benign and 2783 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 P 6 13 19 0.717 0.420 View mutations
352 E 8 11 19 0.581 0.433 View mutations
353 L 2 17 19 0.856 0.388 View mutations
354 A 8 11 19 0.578 0.432 View mutations
355 M 8 11 19 0.558 0.431 View mutations
356 M 17 2 19 0.124 0.573 View mutations
357 H 17 2 19 0.150 0.506 View mutations
358 C 4 15 19 0.776 0.392 View mutations
359 S 3 16 19 0.776 0.435 View mutations
360 Y 18 1 19 0.105 0.425 View mutations
361 W 19 0 19 0.010 0.393 View mutations
362 D 10 9 19 0.537 0.432 View mutations
363 H 1 18 19 0.938 0.387 View mutations
364 D 3 16 19 0.834 0.429 View mutations
365 S 13 6 19 0.326 0.497 View mutations
366 K 15 4 19 0.214 0.501 View mutations
367 T 16 3 19 0.160 0.549 View mutations
368 G 10 9 19 0.511 0.461 View mutations
369 A 19 0 19 0.039 0.543 View mutations
370 L 19 0 19 0.008 0.451 View mutations
371 H 18 1 19 0.107 0.463 View mutations
372 S 19 0 19 0.000 0.502 View mutations
373 R 18 1 19 0.062 0.456 View mutations
374 L 19 0 19 0.032 0.417 View mutations
375 D 19 0 19 0.024 0.473 View mutations