P62841 (RPS15)

Overview
Predicted structure (AF):
AF-P62841-F1-model_v4
Uniprot entry:
P62841
Gene:
RPS15
Protein length:
145 residues
Mutations found:
2754
Benign based on D2Deep prediction:
1473 out of 2754 mutations
Pathogenic based on D2Deep prediction:
1281 out of 2754 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 2754 mutations across 145 unique positions. There are 1473 benign and 1281 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 R 1 18 19 0.932 0.370 View mutations
52 K 2 17 19 0.880 0.358 View mutations
53 Q 4 15 19 0.803 0.433 View mutations
54 H 17 2 19 0.191 0.546 View mutations
55 S 18 1 19 0.124 0.471 View mutations
56 L 5 14 19 0.666 0.555 View mutations
57 L 2 17 19 0.893 0.582 View mutations
58 K 19 0 19 0.046 0.523 View mutations
59 R 13 6 19 0.352 0.432 View mutations
60 L 17 2 19 0.255 0.307 View mutations
61 R 3 16 19 0.823 0.454 View mutations
62 K 8 11 19 0.582 0.428 View mutations
63 A 18 1 19 0.047 0.464 View mutations
64 K 16 3 19 0.248 0.398 View mutations
65 K 17 2 19 0.138 0.634 View mutations
66 E 12 7 19 0.384 0.481 View mutations
67 A 7 12 19 0.533 0.425 View mutations
68 P 19 0 19 0.012 0.691 View mutations
69 P 19 0 19 0.000 0.539 View mutations
70 M 19 0 19 0.001 0.608 View mutations
71 E 7 12 19 0.591 0.519 View mutations
72 K 7 12 19 0.500 0.512 View mutations
73 P 0 19 19 1.000 0.590 View mutations
74 E 11 8 19 0.464 0.450 View mutations
75 V 8 11 19 0.551 0.432 View mutations