P62841 (RPS15)

Overview
Predicted structure (AF):
AF-P62841-F1-model_v4
Uniprot entry:
P62841
Gene:
RPS15
Protein length:
145 residues
Mutations found:
2754
Benign based on D2Deep prediction:
1473 out of 2754 mutations
Pathogenic based on D2Deep prediction:
1281 out of 2754 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 2754 mutations across 145 unique positions. There are 1473 benign and 1281 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 V 2 17 19 0.822 0.631 View mutations
77 K 17 2 19 0.198 0.367 View mutations
78 T 0 19 19 1.000 0.779 View mutations
79 H 0 19 19 0.997 0.882 View mutations
80 L 0 19 19 1.000 0.856 View mutations
81 R 0 19 19 0.981 0.856 View mutations
82 D 1 18 19 0.948 0.779 View mutations
83 M 0 19 19 0.992 0.739 View mutations
84 I 9 10 19 0.551 0.516 View mutations
85 I 1 18 19 0.944 0.817 View mutations
86 L 18 1 19 0.111 0.321 View mutations
87 P 0 19 19 1.000 1.000 View mutations
88 E 0 19 19 0.999 0.977 View mutations
89 M 18 1 19 0.112 0.229 View mutations
90 V 19 0 19 0.032 0.286 View mutations
91 G 14 5 19 0.285 0.310 View mutations
92 S 19 0 19 0.000 0.302 View mutations
93 M 10 9 19 0.482 0.496 View mutations
94 V 14 5 19 0.295 0.410 View mutations
95 G 1 18 19 0.944 0.727 View mutations
96 V 1 18 19 0.948 0.804 View mutations
97 Y 2 17 19 0.898 0.697 View mutations
98 N 10 9 19 0.472 0.488 View mutations
99 G 0 19 19 0.993 0.940 View mutations
100 K 0 19 19 0.883 0.623 View mutations