Q04771 (ACVR1)

Overview
Predicted structure (AF):
AF-Q04771-F1-model_v4
Uniprot entry:
Q04771
Gene:
ACVR1
Protein length:
509 residues
Mutations found:
9670
Benign based on D2Deep prediction:
5151 out of 9670 mutations
Pathogenic based on D2Deep prediction:
4519 out of 9670 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9670 mutations across 509 unique positions. There are 5151 benign and 4519 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
476 E 19 0 19 0.028 0.340 View mutations
477 C 0 19 19 0.979 0.653 View mutations
478 W 18 1 19 0.061 0.401 View mutations
479 Y 0 19 19 0.923 0.558 View mutations
480 Q 10 9 19 0.453 0.499 View mutations
481 N 1 18 19 0.948 0.545 View mutations
482 P 1 18 19 0.959 0.614 View mutations
483 S 16 3 19 0.158 0.484 View mutations
484 A 9 10 19 0.561 0.507 View mutations
485 R 0 19 19 0.996 0.699 View mutations
486 L 0 19 19 1.000 0.673 View mutations
487 T 1 18 19 0.941 0.620 View mutations
488 A 8 11 19 0.563 0.511 View mutations
489 L 19 0 19 0.000 0.363 View mutations
490 R 18 1 19 0.060 0.315 View mutations
491 I 5 14 19 0.744 0.531 View mutations
492 K 16 3 19 0.204 0.390 View mutations
493 K 9 10 19 0.527 0.507 View mutations
494 T 19 0 19 0.000 0.395 View mutations
495 L 1 18 19 0.892 0.596 View mutations
496 T 19 0 19 0.010 0.553 View mutations
497 K 18 1 19 0.064 0.475 View mutations
498 I 2 17 19 0.894 0.456 View mutations
499 D 4 15 19 0.821 0.369 View mutations
500 N 19 0 19 0.020 0.573 View mutations