O14757 (CHEK1) at position 12

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19 mutations found: 5 benign and 14 pathogenic.

D2Deep score mean: 0.743. Overall confidence mean: 0.523

Identifier Original Position Target D2Deep Prediction Pred. Interpretation Overall confidence Actions
V12A V 12 A 0.081 Benign based on D2Deep prediction 0.451 View mutation
V12C V 12 C 0.586 Pathogenic based on D2Deep prediction 0.549 View mutation
V12D V 12 D 0.970 Pathogenic based on D2Deep prediction 0.549 View mutation
V12E V 12 E 0.980 Pathogenic based on D2Deep prediction 0.549 View mutation
V12F V 12 F 0.993 Pathogenic based on D2Deep prediction 0.549 View mutation
V12G V 12 G 0.993 Pathogenic based on D2Deep prediction 0.549 View mutation
V12H V 12 H 1.000 Pathogenic based on D2Deep prediction 0.549 View mutation
V12I V 12 I 0.001 Benign based on D2Deep prediction 0.451 View mutation
V12K V 12 K 0.237 Benign based on D2Deep prediction 0.451 View mutation
V12L V 12 L 0.021 Benign based on D2Deep prediction 0.451 View mutation
V12M V 12 M 0.940 Pathogenic based on D2Deep prediction 0.549 View mutation
V12N V 12 N 0.998 Pathogenic based on D2Deep prediction 0.549 View mutation
V12P V 12 P 1.000 Pathogenic based on D2Deep prediction 0.549 View mutation
V12Q V 12 Q 0.967 Pathogenic based on D2Deep prediction 0.549 View mutation
V12R V 12 R 0.998 Pathogenic based on D2Deep prediction 0.549 View mutation
V12S V 12 S 0.995 Pathogenic based on D2Deep prediction 0.549 View mutation
V12T V 12 T 0.389 Benign based on D2Deep prediction 0.451 View mutation
V12W V 12 W 1.000 Pathogenic based on D2Deep prediction 0.549 View mutation
V12Y V 12 Y 0.964 Pathogenic based on D2Deep prediction 0.549 View mutation