O15315-3 (RAD51B)

Overview
Predicted structure (AF):
AF-O15315-3-F1-model_v4
Uniprot entry:
O15315-3
Gene:
RAD51B
Protein length:
384 residues
Mutations found:
7295
Benign based on D2Deep prediction:
3777 out of 7295 mutations
Pathogenic based on D2Deep prediction:
3518 out of 7295 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 7295 mutations across 384 unique positions. There are 3777 benign and 3518 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 T 11 8 19 0.435 0.432 View mutations
27 C 17 2 19 0.119 0.475 View mutations
28 Q 15 4 19 0.219 0.448 View mutations
29 D 1 18 19 0.961 0.449 View mutations
30 F 0 19 19 0.999 0.566 View mutations
31 L 4 15 19 0.751 0.535 View mutations
32 C 16 3 19 0.188 0.438 View mutations
33 L 0 19 19 0.986 0.515 View mutations
34 S 8 11 19 0.569 0.436 View mutations
35 P 2 17 19 0.840 0.402 View mutations
36 L 14 5 19 0.216 0.398 View mutations
37 E 2 17 19 0.844 0.512 View mutations
38 L 0 19 19 0.999 0.520 View mutations
39 M 0 19 19 0.986 0.478 View mutations
40 K 17 2 19 0.202 0.452 View mutations
41 V 15 4 19 0.210 0.483 View mutations
42 T 5 14 19 0.719 0.436 View mutations
43 G 19 0 19 0.019 0.469 View mutations
44 L 3 16 19 0.840 0.417 View mutations
45 S 0 19 19 0.989 0.396 View mutations
46 Y 1 18 19 0.924 0.369 View mutations
47 R 18 1 19 0.145 0.693 View mutations
48 G 0 19 19 1.000 0.295 View mutations
49 V 1 18 19 0.956 0.430 View mutations
50 H 3 16 19 0.780 0.359 View mutations