O15315-3 (RAD51B)

Overview
Predicted structure (AF):
AF-O15315-3-F1-model_v4
Uniprot entry:
O15315-3
Gene:
RAD51B
Protein length:
384 residues
Mutations found:
7295
Benign based on D2Deep prediction:
3777 out of 7295 mutations
Pathogenic based on D2Deep prediction:
3518 out of 7295 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 7295 mutations across 384 unique positions. There are 3777 benign and 3518 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 13 5 18 0.375 0.500 View mutations
2 G 8 11 19 0.598 0.434 View mutations
3 S 1 18 19 0.932 0.362 View mutations
4 K 1 18 19 0.902 0.461 View mutations
5 K 13 6 19 0.377 0.410 View mutations
6 L 4 15 19 0.820 0.509 View mutations
7 K 19 0 19 0.000 0.394 View mutations
8 R 19 0 19 0.007 0.377 View mutations
9 V 10 9 19 0.415 0.447 View mutations
10 G 8 11 19 0.592 0.431 View mutations
11 L 19 0 19 0.068 0.492 View mutations
12 S 13 6 19 0.315 0.484 View mutations
13 Q 12 7 19 0.360 0.492 View mutations
14 E 5 14 19 0.705 0.404 View mutations
15 L 7 12 19 0.602 0.426 View mutations
16 C 19 0 19 0.021 0.479 View mutations
17 D 7 12 19 0.649 0.436 View mutations
18 R 7 12 19 0.645 0.431 View mutations
19 L 15 4 19 0.285 0.456 View mutations
20 S 19 0 19 0.059 0.518 View mutations
21 R 0 19 19 0.997 0.390 View mutations
22 H 15 4 19 0.230 0.477 View mutations
23 Q 2 17 19 0.926 0.434 View mutations
24 I 0 19 19 0.955 0.482 View mutations
25 L 10 9 19 0.464 0.452 View mutations