O15315-3 (RAD51B)

Overview
Predicted structure (AF):
AF-O15315-3-F1-model_v4
Uniprot entry:
O15315-3
Gene:
RAD51B
Protein length:
384 residues
Mutations found:
7295
Benign based on D2Deep prediction:
3777 out of 7295 mutations
Pathogenic based on D2Deep prediction:
3518 out of 7295 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7295 mutations across 384 unique positions. There are 3777 benign and 3518 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 E 1 18 19 0.948 0.285 View mutations
52 L 0 19 19 0.980 0.425 View mutations
53 L 2 17 19 0.885 0.460 View mutations
54 C 17 2 19 0.122 0.629 View mutations
55 M 14 5 19 0.239 0.540 View mutations
56 V 5 14 19 0.771 0.547 View mutations
57 S 0 19 19 1.000 0.552 View mutations
58 R 16 3 19 0.218 0.543 View mutations
59 A 9 10 19 0.548 0.430 View mutations
60 C 1 18 19 0.890 0.541 View mutations
61 A 1 18 19 0.863 0.535 View mutations
62 P 0 19 19 1.000 0.563 View mutations
63 K 11 8 19 0.494 0.458 View mutations
64 M 7 12 19 0.600 0.435 View mutations
65 Q 17 2 19 0.175 0.499 View mutations
66 T 6 13 19 0.733 0.413 View mutations
67 A 3 16 19 0.835 0.454 View mutations
68 Y 19 0 19 0.060 0.582 View mutations
69 G 19 0 19 0.029 0.637 View mutations
70 I 16 3 19 0.189 0.600 View mutations
71 K 4 15 19 0.823 0.326 View mutations
72 A 18 1 19 0.051 0.743 View mutations
73 Q 13 6 19 0.279 0.621 View mutations
74 R 18 1 19 0.161 0.769 View mutations
75 S 12 7 19 0.342 0.580 View mutations