O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.000 0.532 View mutations
2 R 19 0 19 0.002 0.647 View mutations
3 G 15 4 19 0.236 0.556 View mutations
4 K 19 0 19 0.001 0.629 View mutations
5 T 19 0 19 0.009 0.689 View mutations
6 F 19 0 19 0.006 0.725 View mutations
7 R 19 0 19 0.003 0.740 View mutations
8 F 19 0 19 0.023 0.669 View mutations
9 E 19 0 19 0.001 0.694 View mutations
10 M 11 8 19 0.476 0.493 View mutations
11 Q 19 0 19 0.004 0.660 View mutations
12 R 4 15 19 0.768 0.396 View mutations
13 D 18 1 19 0.055 0.571 View mutations
14 L 5 14 19 0.697 0.433 View mutations
15 V 19 0 19 0.038 0.575 View mutations
16 S 19 0 19 0.000 0.523 View mutations
17 F 9 10 19 0.555 0.442 View mutations
18 P 7 12 19 0.641 0.427 View mutations
19 L 2 17 19 0.868 0.384 View mutations
20 S 16 3 19 0.157 0.446 View mutations
21 P 1 18 19 0.894 0.447 View mutations
22 A 16 3 19 0.176 0.523 View mutations
23 V 9 10 19 0.534 0.441 View mutations
24 R 0 19 19 0.965 0.428 View mutations
25 V 5 14 19 0.724 0.404 View mutations