O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 G 0 19 19 1.000 0.549 View mutations
52 I 1 18 19 0.960 0.563 View mutations
53 S 1 18 19 0.937 0.585 View mutations
54 K 17 2 19 0.171 0.443 View mutations
55 A 19 0 19 0.023 0.422 View mutations
56 E 3 16 19 0.843 0.577 View mutations
57 A 0 19 19 1.000 0.624 View mutations
58 L 18 1 19 0.156 0.447 View mutations
59 E 6 13 19 0.698 0.524 View mutations
60 T 4 15 19 0.789 0.511 View mutations
61 L 1 18 19 0.968 0.587 View mutations
62 Q 5 14 19 0.723 0.425 View mutations
63 I 18 1 19 0.066 0.477 View mutations
64 I 7 12 19 0.643 0.441 View mutations
65 R 5 14 19 0.701 0.399 View mutations
66 R 19 0 19 0.082 0.716 View mutations
67 E 15 4 19 0.217 0.584 View mutations
68 C 19 0 19 0.076 0.773 View mutations
69 L 19 0 19 0.000 0.871 View mutations
70 T 19 0 19 0.001 0.876 View mutations
71 N 19 0 19 0.039 0.922 View mutations
72 K 18 1 19 0.082 0.915 View mutations
73 P 18 1 19 0.080 0.902 View mutations
74 R 19 0 19 0.002 0.992 View mutations
75 Y 19 0 19 0.001 0.978 View mutations