O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 K 2 17 19 0.844 0.419 View mutations
27 L 19 0 19 0.001 0.369 View mutations
28 V 4 15 19 0.689 0.413 View mutations
29 S 15 4 19 0.245 0.479 View mutations
30 A 9 10 19 0.562 0.501 View mutations
31 G 0 19 19 0.955 0.585 View mutations
32 F 5 14 19 0.691 0.516 View mutations
33 Q 8 11 19 0.609 0.434 View mutations
34 T 15 4 19 0.329 0.499 View mutations
35 A 9 10 19 0.491 0.438 View mutations
36 E 19 0 19 0.016 0.511 View mutations
37 E 13 6 19 0.312 0.421 View mutations
38 L 3 16 19 0.847 0.413 View mutations
39 L 12 7 19 0.423 0.499 View mutations
40 E 18 1 19 0.068 0.529 View mutations
41 V 8 11 19 0.573 0.431 View mutations
42 K 19 0 19 0.014 0.620 View mutations
43 P 19 0 19 0.019 0.516 View mutations
44 S 17 2 19 0.118 0.594 View mutations
45 E 2 17 19 0.881 0.368 View mutations
46 L 1 18 19 0.924 0.464 View mutations
47 S 11 8 19 0.356 0.426 View mutations
48 K 4 15 19 0.832 0.421 View mutations
49 E 0 19 19 0.912 0.492 View mutations
50 V 3 16 19 0.809 0.449 View mutations