O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 V 17 2 19 0.119 0.803 View mutations
352 T 19 0 19 0.011 0.916 View mutations
353 S 19 0 19 0.006 0.970 View mutations
354 A 19 0 19 0.021 0.940 View mutations
355 C 19 0 19 0.002 0.982 View mutations
356 S 19 0 19 0.000 0.967 View mutations
357 L 19 0 19 0.001 0.939 View mutations
358 Q 19 0 19 0.016 0.919 View mutations
359 T 19 0 19 0.012 0.923 View mutations
360 E 19 0 19 0.000 0.910 View mutations
361 G 19 0 19 0.001 0.917 View mutations
362 S 19 0 19 0.020 0.922 View mutations
363 L 8 11 19 0.527 0.423 View mutations
364 S 13 6 19 0.300 0.624 View mutations
365 T 18 1 19 0.095 0.812 View mutations
366 R 16 3 19 0.150 0.734 View mutations
367 K 19 0 19 0.038 0.768 View mutations
368 R 9 10 19 0.606 0.449 View mutations
369 S 18 1 19 0.074 0.691 View mutations
370 R 19 0 19 0.040 0.745 View mutations
371 D 17 2 19 0.128 0.731 View mutations
372 P 19 0 19 0.009 0.860 View mutations
373 E 18 1 19 0.129 0.857 View mutations
374 E 18 1 19 0.039 0.862 View mutations
375 E 18 1 19 0.035 0.798 View mutations