O43502 (O43502)

Overview
Predicted structure (AF):
AF-O43502-F1-model_v4
Uniprot entry:
O43502
Gene:
O43502
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4034 out of 7143 mutations
Pathogenic based on D2Deep prediction:
3109 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7143 mutations across 376 unique positions. There are 4034 benign and 3109 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 L 11 8 19 0.486 0.427 View mutations
327 Y 16 3 19 0.185 0.462 View mutations
328 K 10 9 19 0.481 0.496 View mutations
329 S 8 11 19 0.496 0.508 View mutations
330 P 7 12 19 0.597 0.510 View mutations
331 S 3 16 19 0.863 0.423 View mutations
332 Q 17 2 19 0.140 0.427 View mutations
333 K 19 0 19 0.011 0.564 View mutations
334 E 12 7 19 0.375 0.441 View mutations
335 C 18 1 19 0.053 0.518 View mutations
336 T 19 0 19 0.000 0.496 View mutations
337 V 19 0 19 0.000 0.499 View mutations
338 L 19 0 19 0.000 0.573 View mutations
339 F 19 0 19 0.003 0.434 View mutations
340 Q 16 3 19 0.156 0.565 View mutations
341 I 19 0 19 0.000 0.360 View mutations
342 K 16 3 19 0.176 0.510 View mutations
343 P 19 0 19 0.022 0.588 View mutations
344 Q 13 6 19 0.297 0.522 View mutations
345 G 19 0 19 0.000 0.482 View mutations
346 F 19 0 19 0.005 0.359 View mutations
347 R 17 2 19 0.130 0.498 View mutations
348 D 4 15 19 0.766 0.364 View mutations
349 T 16 3 19 0.146 0.690 View mutations
350 V 19 0 19 0.007 0.869 View mutations