P06748 (NPM1) at position 12

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19 mutations found: 16 benign and 3 pathogenic.

D2Deep score mean: 0.221. Overall confidence mean: 0.381

Identifier Original Position Target D2Deep Prediction Pred. Interpretation Overall confidence Actions
L12A L 12 A 0.006 Benign based on D2Deep prediction 0.325 View mutation
L12C L 12 C 0.923 Pathogenic based on D2Deep prediction 0.675 View mutation
L12D L 12 D 0.012 Benign based on D2Deep prediction 0.325 View mutation
L12E L 12 E 0.862 Pathogenic based on D2Deep prediction 0.675 View mutation
L12F L 12 F 0.016 Benign based on D2Deep prediction 0.325 View mutation
L12G L 12 G 0.011 Benign based on D2Deep prediction 0.325 View mutation
L12H L 12 H 0.026 Benign based on D2Deep prediction 0.325 View mutation
L12I L 12 I 0.031 Benign based on D2Deep prediction 0.325 View mutation
L12K L 12 K 0.418 Benign based on D2Deep prediction 0.325 View mutation
L12M L 12 M 0.137 Benign based on D2Deep prediction 0.325 View mutation
L12N L 12 N 0.001 Benign based on D2Deep prediction 0.325 View mutation
L12P L 12 P 0.001 Benign based on D2Deep prediction 0.325 View mutation
L12Q L 12 Q 0.918 Pathogenic based on D2Deep prediction 0.675 View mutation
L12R L 12 R 0.292 Benign based on D2Deep prediction 0.325 View mutation
L12S L 12 S 0.081 Benign based on D2Deep prediction 0.325 View mutation
L12T L 12 T 0.098 Benign based on D2Deep prediction 0.325 View mutation
L12V L 12 V 0.002 Benign based on D2Deep prediction 0.325 View mutation
L12W L 12 W 0.355 Benign based on D2Deep prediction 0.325 View mutation
L12Y L 12 Y 0.013 Benign based on D2Deep prediction 0.325 View mutation