P06748 (NPM1) at position 18

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19 mutations found: 7 benign and 12 pathogenic.

D2Deep score mean: 0.666. Overall confidence mean: 0.529

Identifier Original Position Target D2Deep Prediction Pred. Interpretation Overall confidence Actions
L18A L 18 A 0.399 Benign based on D2Deep prediction 0.390 View mutation
L18C L 18 C 0.272 Benign based on D2Deep prediction 0.390 View mutation
L18D L 18 D 0.577 Pathogenic based on D2Deep prediction 0.610 View mutation
L18E L 18 E 0.805 Pathogenic based on D2Deep prediction 0.610 View mutation
L18F L 18 F 0.896 Pathogenic based on D2Deep prediction 0.610 View mutation
L18G L 18 G 0.940 Pathogenic based on D2Deep prediction 0.610 View mutation
L18H L 18 H 0.181 Benign based on D2Deep prediction 0.390 View mutation
L18I L 18 I 0.112 Benign based on D2Deep prediction 0.390 View mutation
L18K L 18 K 0.999 Pathogenic based on D2Deep prediction 0.610 View mutation
L18M L 18 M 0.999 Pathogenic based on D2Deep prediction 0.610 View mutation
L18N L 18 N 0.147 Benign based on D2Deep prediction 0.390 View mutation
L18P L 18 P 0.996 Pathogenic based on D2Deep prediction 0.610 View mutation
L18Q L 18 Q 0.866 Pathogenic based on D2Deep prediction 0.610 View mutation
L18R L 18 R 0.999 Pathogenic based on D2Deep prediction 0.610 View mutation
L18S L 18 S 0.983 Pathogenic based on D2Deep prediction 0.610 View mutation
L18T L 18 T 0.992 Pathogenic based on D2Deep prediction 0.610 View mutation
L18V L 18 V 0.454 Benign based on D2Deep prediction 0.390 View mutation
L18W L 18 W 0.946 Pathogenic based on D2Deep prediction 0.610 View mutation
L18Y L 18 Y 0.086 Benign based on D2Deep prediction 0.390 View mutation