P06748 (NPM1) at position 25

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19 mutations found: 8 benign and 11 pathogenic.

D2Deep score mean: 0.534. Overall confidence mean: 0.530

Identifier Original Position Target D2Deep Prediction Pred. Interpretation Overall confidence Actions
A25C A 25 C 0.112 Benign based on D2Deep prediction 0.312 View mutation
A25D A 25 D 0.848 Pathogenic based on D2Deep prediction 0.688 View mutation
A25E A 25 E 0.743 Pathogenic based on D2Deep prediction 0.688 View mutation
A25F A 25 F 0.950 Pathogenic based on D2Deep prediction 0.688 View mutation
A25G A 25 G 0.062 Benign based on D2Deep prediction 0.312 View mutation
A25H A 25 H 0.518 Pathogenic based on D2Deep prediction 0.688 View mutation
A25I A 25 I 0.484 Benign based on D2Deep prediction 0.312 View mutation
A25K A 25 K 0.992 Pathogenic based on D2Deep prediction 0.688 View mutation
A25L A 25 L 0.730 Pathogenic based on D2Deep prediction 0.688 View mutation
A25M A 25 M 0.381 Benign based on D2Deep prediction 0.312 View mutation
A25N A 25 N 0.612 Pathogenic based on D2Deep prediction 0.688 View mutation
A25P A 25 P 0.163 Benign based on D2Deep prediction 0.312 View mutation
A25Q A 25 Q 0.867 Pathogenic based on D2Deep prediction 0.688 View mutation
A25R A 25 R 0.540 Pathogenic based on D2Deep prediction 0.688 View mutation
A25S A 25 S 0.011 Benign based on D2Deep prediction 0.312 View mutation
A25T A 25 T 0.025 Benign based on D2Deep prediction 0.312 View mutation
A25V A 25 V 0.181 Benign based on D2Deep prediction 0.312 View mutation
A25W A 25 W 0.986 Pathogenic based on D2Deep prediction 0.688 View mutation
A25Y A 25 Y 0.944 Pathogenic based on D2Deep prediction 0.688 View mutation