P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 T 5 14 19 0.760 0.460 View mutations
77 A 18 1 19 0.073 0.359 View mutations
78 I 1 18 19 0.974 0.529 View mutations
79 A 8 11 19 0.634 0.436 View mutations
80 P 5 14 19 0.729 0.448 View mutations
81 L 0 19 19 0.992 0.526 View mutations
82 D 8 11 19 0.585 0.436 View mutations
83 G 2 17 19 0.897 0.530 View mutations
84 E 17 2 19 0.160 0.468 View mutations
85 E 1 18 19 0.910 0.529 View mutations
86 L 17 2 19 0.127 0.423 View mutations
87 I 16 3 19 0.250 0.403 View mutations
88 V 4 15 19 0.755 0.583 View mutations
89 E 16 3 19 0.196 0.463 View mutations
90 V 19 0 19 0.013 0.404 View mutations
91 L 16 3 19 0.144 0.463 View mutations
92 E 19 0 19 0.000 0.375 View mutations
93 D 14 5 19 0.247 0.484 View mutations
94 V 19 0 19 0.013 0.391 View mutations
95 P 0 19 19 0.998 0.627 View mutations
96 L 0 19 19 0.929 0.606 View mutations
97 T 9 10 19 0.514 0.507 View mutations
98 M 13 6 19 0.386 0.458 View mutations
99 H 17 2 19 0.101 0.357 View mutations
100 N 5 14 19 0.736 0.583 View mutations