P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.007 0.598 View mutations
2 L 18 1 19 0.071 0.711 View mutations
3 L 15 4 19 0.285 0.622 View mutations
4 S 19 0 19 0.031 0.729 View mutations
5 K 19 0 19 0.005 0.748 View mutations
6 I 18 1 19 0.054 0.780 View mutations
7 N 19 0 19 0.008 0.813 View mutations
8 S 19 0 19 0.002 0.835 View mutations
9 L 19 0 19 0.009 0.851 View mutations
10 A 19 0 19 0.007 0.855 View mutations
11 H 19 0 19 0.001 0.890 View mutations
12 L 19 0 19 0.004 0.877 View mutations
13 R 19 0 19 0.002 1.000 View mutations
14 A 19 0 19 0.010 0.950 View mutations
15 A 19 0 19 0.002 0.923 View mutations
16 P 19 0 19 0.001 0.947 View mutations
17 C 19 0 19 0.001 0.914 View mutations
18 N 19 0 19 0.028 0.943 View mutations
19 D 18 1 19 0.034 0.817 View mutations
20 L 19 0 19 0.001 0.839 View mutations
21 H 18 1 19 0.063 0.837 View mutations
22 A 19 0 19 0.003 0.830 View mutations
23 T 19 0 19 0.011 0.856 View mutations
24 K 19 0 19 0.010 0.899 View mutations
25 L 19 0 19 0.027 0.870 View mutations