P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 A 19 0 19 0.004 0.886 View mutations
27 P 19 0 19 0.001 0.848 View mutations
28 G 19 0 19 0.002 0.785 View mutations
29 K 19 0 19 0.017 0.815 View mutations
30 E 19 0 19 0.012 0.786 View mutations
31 K 19 0 19 0.004 0.716 View mutations
32 E 19 0 19 0.001 0.617 View mutations
33 P 19 0 19 0.032 0.741 View mutations
34 L 19 0 19 0.093 0.619 View mutations
35 E 18 1 19 0.051 0.629 View mutations
36 S 19 0 19 0.002 0.662 View mutations
37 Q 19 0 19 0.001 0.626 View mutations
38 Y 0 19 19 0.998 0.317 View mutations
39 Q 17 2 19 0.133 0.597 View mutations
40 V 9 10 19 0.464 0.445 View mutations
41 G 5 14 19 0.661 0.404 View mutations
42 P 19 0 19 0.001 0.615 View mutations
43 L 19 0 19 0.000 0.586 View mutations
44 L 3 16 19 0.825 0.447 View mutations
45 G 0 19 19 1.000 0.520 View mutations
46 S 4 15 19 0.785 0.436 View mutations
47 G 4 15 19 0.810 0.538 View mutations
48 G 0 19 19 0.991 0.527 View mutations
49 F 0 19 19 0.998 0.477 View mutations
50 G 0 19 19 1.000 0.620 View mutations