P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 S 1 18 19 0.947 0.452 View mutations
52 V 0 19 19 0.997 0.530 View mutations
53 Y 1 18 19 0.948 0.428 View mutations
54 S 8 11 19 0.572 0.435 View mutations
55 G 18 1 19 0.038 0.389 View mutations
56 I 16 3 19 0.212 0.504 View mutations
57 R 0 19 19 0.976 0.452 View mutations
58 V 18 1 19 0.068 0.515 View mutations
59 S 19 0 19 0.008 0.446 View mutations
60 D 1 18 19 0.961 0.434 View mutations
61 N 15 4 19 0.242 0.485 View mutations
62 L 15 4 19 0.285 0.473 View mutations
63 P 19 0 19 0.006 0.472 View mutations
64 V 16 3 19 0.131 0.475 View mutations
65 A 10 9 19 0.495 0.424 View mutations
66 I 4 15 19 0.698 0.426 View mutations
67 K 0 19 19 0.998 0.346 View mutations
68 H 9 10 19 0.509 0.447 View mutations
69 V 19 0 19 0.042 0.451 View mutations
70 E 19 0 19 0.002 0.613 View mutations
71 K 3 16 19 0.819 0.374 View mutations
72 D 18 1 19 0.080 0.490 View mutations
73 R 13 6 19 0.419 0.492 View mutations
74 I 8 11 19 0.499 0.434 View mutations
75 S 17 2 19 0.107 0.561 View mutations