P11487 (P11487)

Overview
Predicted structure (AF):
AF-P11487-F1-model_v4
Uniprot entry:
P11487
Gene:
P11487
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
1978 out of 4540 mutations
Pathogenic based on D2Deep prediction:
2562 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4540 mutations across 239 unique positions. There are 1978 benign and 2562 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 Q 4 15 19 0.797 0.291 View mutations
227 A 19 0 19 0.004 0.788 View mutations
228 S 17 2 19 0.157 0.718 View mutations
229 R 8 11 19 0.598 0.426 View mutations
230 L 15 4 19 0.268 0.653 View mutations
231 G 17 2 19 0.127 0.682 View mutations
232 S 13 6 19 0.327 0.565 View mutations
233 Q 3 16 19 0.816 0.290 View mutations
234 L 7 12 19 0.590 0.406 View mutations
235 E 16 3 19 0.204 0.626 View mutations
236 A 19 0 19 0.053 0.706 View mutations
237 S 15 4 19 0.262 0.614 View mutations
238 A 5 14 19 0.710 0.359 View mutations
239 H 3 16 19 0.811 0.344 View mutations