P11487 (P11487)

Overview
Predicted structure (AF):
AF-P11487-F1-model_v4
Uniprot entry:
P11487
Gene:
P11487
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
1978 out of 4540 mutations
Pathogenic based on D2Deep prediction:
2562 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4540 mutations across 239 unique positions. There are 1978 benign and 2562 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.045 0.656 View mutations
2 G 17 2 19 0.092 0.767 View mutations
3 L 5 14 19 0.711 0.321 View mutations
4 I 18 1 19 0.123 0.795 View mutations
5 W 19 0 19 0.015 0.825 View mutations
6 L 19 0 19 0.009 0.851 View mutations
7 L 18 1 19 0.057 0.772 View mutations
8 L 19 0 19 0.005 0.843 View mutations
9 L 17 2 19 0.076 0.765 View mutations
10 S 19 0 19 0.021 0.828 View mutations
11 L 19 0 19 0.043 0.798 View mutations
12 L 10 9 19 0.543 0.500 View mutations
13 E 19 0 19 0.042 0.855 View mutations
14 P 19 0 19 0.061 0.916 View mutations
15 G 19 0 19 0.007 0.994 View mutations
16 W 19 0 19 0.002 0.938 View mutations
17 P 19 0 19 0.004 0.950 View mutations
18 A 19 0 19 0.091 0.989 View mutations
19 A 19 0 19 0.030 1.000 View mutations
20 G 19 0 19 0.074 0.890 View mutations
21 P 19 0 19 0.075 0.930 View mutations
22 G 19 0 19 0.014 0.878 View mutations
23 A 13 6 19 0.357 0.594 View mutations
24 R 5 14 19 0.753 0.336 View mutations
25 L 16 3 19 0.168 0.663 View mutations